about five years ago I started on celxa, an antidepressant, then I developed gerd, which was either a side effect of celexa or the anxiety I had at the time, and have been on prilosec or prevacid ever since. I always thought it was the celexa and the combination of tea or soda, I know if I give up soda and tea most of my problems with acid reflex would be gone, but I love my soda and I love my iced tea and my caffinee. I don't drink or smoke so I feel like I shouldn't have to give it up but in the long run it's alot of money spend on meds just to drink my drinks. anway, I gained thirty or fourty pounds but I can't say if it's the anti-depressat or the Prilosec. You've given me a new road to research.......